A Cuff-Shaped Enzymeless Glucose Sensor Integrated with Chronically Implantable Peripheral Nerve Cuff Electrode for Inflammation Monitoring

Lee, Yi Jae ;   Park, Sung Jin ;   Kang, Ji Yoon ;   Lee, Soo Hyun

Tags Neural interfaces – Microelectrode and fabrication technologiesNeural interfaces – Sensors and body interfacesNeural interfaces – Implantable systems

This paper reports on a recently developed cuff-shaped enzymeless glucose sensor integrated with chronically implantable peripheral nerve...

Read More Download this Paper

A Fully Implantable and Rechargeable Neurostimulation System for Animal Research

Paralikar, Kunal ;   Santa, Wesley ;   Iyer, Rajesh ;   Thom, Andrew ;   Xin, Su ;   Erik, Hovland ;   Dinsmoor, David ;   Munns, Gordon ;   May, Steven ;   Scott, Erik ;   Denison, Timothy

Tags Neural interfaces – Implantable systemsNeural interfaces – Neural stimulationNeural interfaces – Neural microsystems and interface engineering

A neurostimulation system consisting of a reusable, four-channel, fully-implantable rechargeable neurostimulator (INS), recharger and wireless...

Read More Download this Paper

A Low-Cost, 61-Channel ? ECoG Array for use in Rodents

Woods, Virginia ;   Wang, Charles ;   Bossi, Silvia ;   Insanally, Michele ;   Trumpis, Michael ;   Froemke, Robert ;   Viventi, Jonathan

Tags Neural interfaces – Microelectrode and fabrication technologies

Micro-Electrocorticography (µECoG) offers a minimally invasive, high resolution interface with large areas of cortex. A wide variety of µECoG...

Read More Download this Paper

A Low-Power, Low-Area Modular Architecture for High Density Neural Probes

Angotzi, Gian Nicola ;   Berdondini, Luca

Tags Neural interfaces – Implantable systemsNeural interfaces – Neural microsystems and interface engineeringNeural interfaces – Microelectrode and fabrication technologies

The integration of a novel generation of implantable multi-electrode array probes based on CMOS technology is an emerging approach for...

Read More Download this Paper

A Micro-Scale, Flexible, High-Density Electrode Array for Performing Multi and Single Motor Unit Electromyographic Recordings

Kyle, Srivastava ;   Sober, Samuel

Tags Neural interfaces – Microelectrode and fabrication technologiesMotor learning, neural control, and neuromuscular systemsNeuromuscular systems – EMG models, processing and applications

Electromyography (EMG) provides researchers and clinicians with a window into the activity of individual muscles. This technique is often...

Read More Download this Paper

A Novel Parameter Identification Algorithm for Ionic Conductances Highlights the Role of Ih Current

Michel, Christophe Bernard ;   Desmadryl, Gilles ;   Graham, Bruce Philip

Tags Neural interfaces – Computational modeling and simulationBrain physiology and modeling – Neuron modeling and simulationHuman performance – Modelling and prediction

A computational study of neuronal activity requires good identification of the ionic conductance parameters that shape the electrical...

Read More Download this Paper

A Super Multi-Channel Recording System with UWB Wireless Transmitter and Flexible Electrode Array for BMI

Suzuki, Takafumi ;   Doi, Keiichi ;   Takizawa, Kenichi ;   Hirata, Masayuki ;   Ando, Hiroshi

Tags Brain-computer/machine interfaceNeural interfaces – Implantable systemsNeural interfaces – Neural microsystems and interface engineering

In order to realize a low-invasive and high accuracy BMI system for clinical applications, we developed a multi-channel recording system in which...

Read More Download this Paper

A User-Friendly Wearable Single-Channel EOG-Based Human-Computer Interface for Cursor Control

Ang, Man Shun ;   Zhang, Zhiguo ;   Hung, Y.S. ;   Mak, Joe

Tags Neural interfaces – Sensors and body interfacesNeuromuscular systems – Wearable systems

This paper presents a novel wearable single-channel electrooculography (EOG) based human-computer interface (HCI) with a simple system...

Read More Download this Paper

A Wireless Fully Implantable ECoG Recording Medical Device WIMAGINE® for Human Brain Computer Interface Applications: Toward a Clinical Trial

Charvet, Guillaume ;   Mestais, Corinne ;   Sauter-Starace, Fabien ;   Foerster, Michael ;   Lambert, Aurélien ;   Chabrol, Claude ;   Torres-Martinez, Napoleon ;   Costecalde, Thomas ;   Ratel, David ;   Benabid, Alim-Louis

Tags Neural interfaces – Implantable systemsBrain-computer/machine interfaceMotor neuroprostheses – Robotics

Read More Download this Paper

Analysis of a Baroreflex Model for the Study of the Chronotropic Response to Vagal Nerve Stimulation

Ojeda, David ;   Le Rolle, Virginie ;   Rossel, Olivier ;   Karam, Nicole ;   Hagège, Albert ;   Bonnet, Jean-Luc ;   Mabo, Philippe ;   Carrault, Guy ;   Hernández, Alfredo I

Tags Neural interfaces – Computational modeling and simulationNeural interfaces – Neural stimulationNeural interfaces – Implantable systems

This paper describes the integration of computational models of the cardiovascular system, the cardiac electrical activity and the...

Read More Download this Paper

Axonal Growth Guidance by Surface Nano-Topology for the Regeneration of Sensori Motor Neurons

Charlot, Benoit ;   Lechelon, Mathias ;   Bardin, Fabrice ;   Teissier, Roland ;   Paris, Lambert ;   Valmier, Jean

Tags Neural interfaces – Neural microsystems and interface engineeringNeural interfaces – Sensors and body interfacesNeural interfaces – Biomaterials

Mechanotransduction is the cellular mechanism by which cells, including neurons, sense and respond to their physical surroundings. Cells sense...

Read More Download this Paper

Bidirectional Communications in Wireless Microstimulators based on Electronic Rectification of Epidermically Applied Currents

Becerra-Fajardo, Laura ;   Ivorra, Antoni

Tags Motor neuroprostheses – Neuromuscular stimulationNeural interfaces – Sensors and body interfacesNeural interfaces – Implantable systems

Functional Electrical Stimulation (FES) has been used in order to restore muscle functions in patients suffering from neurological disorders....

Read More Download this Paper

Biocompatibility Evaluation of Parylene C and Polyimide as Substrates for Peripheral Nerve Interfaces

del Valle, Jaume ;   de la Oliva, Natàlia ;   Mueller, Matthias ;   Stieglitz, Thomas ;   Navarro, Xavier

Tags Neural interfaces – BiomaterialsNeural interfaces – Regeneration and tissue-electrode interfaceNeural interfaces – Microelectrode and fabrication technologies

For assessing the suitability of a given material for peripheral nerve implantation, acute and chronic tests to investigate tissue reaction,...

Read More Download this Paper

Calcium Imaging of Retinal Ganglion Cell Dendritic Responses to Extracellular Microelectrode Stimulation

Yang, Chih-Yu ;   Woolley, Andrew ;   Tsai, David ;   Suaning, Gregg ;   Morley, John William ;   Lovell, Nigel H.

Tags Sensory neuroprostheses – VisualNeural interfaces – Neural stimulation

In order to successfully perform electrical stimulation and drive prosthetic vision, it is essential to assess stimulation effectiveness by...

Read More Download this Paper

Carbon Material: New Interface for Next Generation of Neuronal Implants

Rousseau, Lionel ;   Hébert, Clément ;   Cottance, Myline ;   Scorsone, Emmanuel ;   PIRET, Gaelle ;   Lissorgues, Gaelle ;   Yvert, Blaise ;   Picaud, Serge ;   Bergonzo, Philippe

Tags Neural interfaces – Microelectrode and fabrication technologiesNeural interfaces – Implantable systemsNeural interfaces – Biomaterials

In neurology, the use of miniaturized electrodes has led to less invasive recording and stimulating devices. However, the presence of foreign...

Read More Download this Paper

Chronic Thresholds for Evoking Perceptual Responses in the Rat Sensory Cortex

Brunton, Emma Kate ;   Yan, Edwin ;   Gillespie-Jones, Katherine ;   Lowery, Arthur James ;   Rajan, Ramesh

Tags Neural interfaces – Neural stimulationSensory neuroprostheses – VisualBrain-computer/machine interface

Stimulation of neural tissue for the remediation of brain and sensory deficits requires that stimulation paradigms are selected carefully to...

Read More Download this Paper

Combined Neural Measurement with Surface and Depth Microelectrode Array for Topographic and Layer-Specific Characterization in the Auditory Cortex and Thalamus

Shiramatsu, Tomoyo ;   Takahashi, Kazusa ;   Noda, Takahiro ;   Kanzaki, Ryohei ;   Nakahra, Haruka ;   Takahashi, Hirokazu

Tags Neural interfaces – Microelectrode and fabrication technologiesSensory neuroprostheses – Auditory

Interaction between bottom-up and top-down information processing between the auditory cortex (AC) and thalamus (medial geniculate body;...

Read More Download this Paper

Combined Peripheral Nerve and Epidural Spinal Cord Stimulation for a Refined Locomotor Rehabilitation after Paralysis – A Pilot Study

Wurth, Sophie Marie ;   Kinany, Nawal ;   Gandar, Jerome ;   Courtine, Gregoire ;   Micera, Silvestro

Tags Motor neuroprosthesesNeural interfaces – Neural stimulationNeuromuscular systems – Peripheral mechanisms

Electrical epidural stimulation (EES) of the lumbo-sacral spinal cord has been shown to promote locomotion rehabilitation in rodents and humans...

Read More Download this Paper

Comparison of Long-Term Decoding Stability of Ultra High Frequency Band Local Field Potentials (>500Hz) and Spike Signals in Primate Motor Cortex

Jin, Yile ;   Zhang, Qiaosheng ;   Li, Yue ;   Sun, Guanghao ;   Zhu, Junming ;   Zhang, Shaomin ;   Zheng, Xiaoxiang

Tags Brain-computer/machine interfaceNeural signal processing

It has been widely reported that the local field potentials (LFPs) can be a useful signal for neural decoding as well as the spike in the...

Read More Download this Paper

Comparison of the Electrochemical Properties of Smooth and Porous TiN Electrode Coatings in Rats

Meijs, Suzan ;   Sørensen, Charlotte ;   Sørensen, Søren ;   Rechendorff, Kristian ;   Fjorback, Morten ;   Rijkhoff, Nico

Tags Neural interfaces – Neural stimulationNeural interfaces – Neural microsystems and interface engineeringNeural interfaces – Regeneration and tissue-electrode interface

Eight smooth and 8 porous titanium nitride (TiN) coated electrodes were implanted in 8 rats. Before implantation, voltage transients (VTs),...

Read More Download this Paper

Complex, Multilayer Liquid Crystal Polymer Lead Structures Qualified for Direct Biocompatible Implants

Bihler, Eckardt ;   Schulze, Daniel ;   Toelke, Rene ;   Bagen, Susan

Tags Neural interfaces – Implantable systemsNeural interfaces – BiomaterialsNeural interfaces – Microelectrode and fabrication technologies

Miniaturization of implanted medical devices including leads drives the need for directly implantable structures that are inherently...

Read More Download this Paper

Control of Intraspinal Microstimulation using an Adaptive Terminal-Based Neuro-Sliding Mode Control

Rouhani, Ehsan ;   Erfanian, Abbas

Tags Neural interfaces – Neural stimulationMotor learning, neural control, and neuromuscular systemsMotor neuroprostheses – Neuromuscular stimulation

In this study, a terminal-based neuro-sliding mode control was presented for control of ankle joint movement using intraspinal microstimulation...

Read More Download this Paper

Development of a Single-Sided Parylene C based Intrafascicular Multichannel Electrode for Peripheral Nerves

Mueller, Matthias ;   Ulloa Suarez, Miguel Angel ;   Schuettler, Martin ;   Stieglitz, Thomas

Tags Neural interfaces – Microelectrode and fabrication technologiesNeural interfaces – BiomaterialsNeural interfaces – Sensors and body interfaces

As cleanroom fabricated polyimide based electrodes are commonly used in clinical trials due to their small dimensions and high flexibility we want...

Read More Download this Paper

Effects of Different Configurations of Multi-Contact Cuff Electrode on Recruitment Characteristics of Nerve Stimulation

Tao, Wanjun ;   Wang, Zhigong ;   Lü, Xiaoying ;   Gao, Yujie

Tags Neural interfaces – Neural stimulationNeuromuscular systems – EMG models, processing and applications

By quantitatively analyzing the effects of different configurations, it is possible to find the best configuration and further optimize neural...

Read More Download this Paper

Effects of Stratum Corneum and Conductive Gel Properties on Sensory Afferents Recruitment by 3D TENS Computational Modeling

Zhu, Kaihua ;   Li, Peng ;   Chai, Guohong ;   Sui, Xiaohong

Tags Neural interfaces – Computational modeling and simulationNeural interfaces – Neural stimulationSensory neuroprostheses

Abstract?Incorporation of tactile sensory feedback by non-invasive transcutaneous electrical nerve stimulation (TENS) is potentially helpful...

Read More Download this Paper

Electrical Stimulation of Retinal Neurons using an Array of 1024 Capacitive Stimulation Sites

Zeck, Günther

Tags Sensory neuroprostheses – VisualNeural interfaces – Neural stimulationNeural interfaces – Microelectrode and fabrication technologies

Towards improved applications of electrical stimulation it is essential to better understand the cellular and remote effects of this method....

Read More Download this Paper

Evaluation of Thin-Film Temperature Sensors for Integration in Neural Probes

Fiedler, Eva ;   Porto Cruz, Maria Francisca ;   Cota Monjaras, Oscar Fernando ;   Stieglitz, Thomas

Tags Neural interfaces – Sensors and body interfacesNeural interfaces – Microelectrode and fabrication technologies

In situ monitoring of tissue temperature during in vivo experiments can be of great advantage. It could allow the detection of inflammation...

Read More Download this Paper

Fabrication and Implantation of Hydrogel Coated, Flexible Polyimide Electrodes

Hassler, Christina ;   Ehler, Nils ;   Singh, Vivek ;   Xie, Yijing ;   Martini, Nadja ;   Kirch, Robert ;   Prucker, Oswald ;   Rühe, Jürgen ;   Hofmann, Ulrich G. ;   Stieglitz, Thomas

Tags Neural interfaces – Microelectrode and fabrication technologiesNeural interfaces – Neural microsystems and interface engineeringNeural interfaces – Regeneration and tissue-electrode interface

Within this study, flexible, polyimide based shaft electrodes were fabricated and dip-coated with a PDMAA-co-SSAz solution that formed a thin...

Read More Download this Paper

Fabrication and Verification of a Liquid Crystal Polymer (LCP)-Based Retinal Prosthesis

Seo, Jong Mo ;   Chung, Hum ;   Jeong, Joonsoo ;   Bae, So Hyun ;   Min, Kyou Sik ;   Kim, Sung June

Tags Sensory neuroprostheses – VisualNeural interfaces – Biomaterials

A retinal prosthesis is a biomedical implant for vision restoration in blind patients suffering from retinal degeneration. A novel all-polymer...

Read More Download this Paper

Flexible Parylene-Based Neural Probe with Optimized Silk Coating Structure for Improved Insertion in the Brain

Lecomte, Aziliz ;   Descamps, Emeline ;   Dahan, Lionel ;   Blatché, Marie-Charline ;   Bergaud, Christian

Tags Neural interfaces – BiomaterialsNeural interfaces – Microelectrode and fabrication technologiesNeural interfaces – Implantable systems

The use of soft materials as substrate for implantable microelectrodes aims at achieving better compliance with the surrounding neurons while...

Read More Download this Paper

Frequency-Dependent Simulation of Volume Conduction in a Linear Model of the Implanted Cochlea

Inguva, Chidrupi Shilpitha ;   Wong, Paul ;   Sue, Andrian ;   McEwan, Alistair ;   Carter, Paul Michael

Tags Neural interfaces – Computational modeling and simulationSensory neuroprostheses – AuditoryNeural interfaces – Neural stimulation

Volume conduction models of the implanted cochlea are useful tools for investigating cochlear implant function. To date, however, all existing...

Read More Download this Paper

Gold Nanorod Mediated Photothermal Inhibition of Neural Activity

Yoo, Sangjin ;   Park, Ji Ho ;   Nam, Yoonkey

Tags Neural interfaces – Neural stimulationNeural interfaces – Microelectrode and fabrication technologiesNeural interfaces – Neural microsystems and interface engineering

Optical stimulation combined with genetic modification has been introduced as an alternative method for the selective stimulation technique due...

Read More Download this Paper

Imaging of Haemodynamic Spinal Cord Activity in the Pig

Tsiakaka, Olivier ;   Romain, Olivier ;   Benali, Habib ;   Pradat, Pierre-Francois ;   Feruglio, Feruglio

Tags Neural interfaces – NeuroimagingNeural signal processing

Measurement of photoplethysmographic (PPG) signal is widely used to assess metabolic conditions of monitored tissues. Probes were designed to...

Read More Download this Paper

Improving the Brain Machine Interface via Multiple Tetramethyl Orthosilicate Sol-Gel Coatings on Microelectrode Arrays

McDermott, Matthew ;   Zhang, Johnny ;   Otto, Kevin

Tags Neural interfaces – BiomaterialsBrain-computer/machine interface

The failure of neurally implanted microelectrode arrays has been highly correlated with the foreign body response (FBR). In order to maintain...

Read More Download this Paper

In Vitro Biological Assessment of Electrode Materials for Neural Interfaces

Gilmour, Aaron ;   Goding, Josef ;   Poole-Warren, Laura A. ;   Thomson, Christine ;   Green, Rylie Adelle

Tags Neural interfaces – BiomaterialsBrain-computer/machine interface

The development of the next generation electrode interfaces for neural prosthetic devices requires high-throughput multifaceted testing...

Read More Download this Paper

In-Vivo Characterization of a 0.8 – 3 µVRMS Input-Noise Versatile CMOS Pre-Amplifier

Cota Monjaras, Oscar Fernando ;   Plachta, Dennis T.T. ;   Stieglitz, Thomas ;   Manoli, Yiannos ;   Kuhl, Matthias

Tags Neural interfaces – Neural microsystems and interface engineeringNeural interfaces – Implantable systemsNeural signal processing

The following work presents a CMOS-integrated low-noise pre-amplifier (LNA) for bio-potential recordings, which is part of a multi-channel...

Read More Download this Paper

In-Vivo Tests of a 16-Channel Implantable Wireless Neural Stimulator

Troyk, Philip ;   Bredeson, Samuel ;   Cogan, Stuart ;   Romero-Ortega, Mario Ignacio ;   Suh, Sungjae ;   Hu, Zhe ;   Kanneganti, Aswini ;   Granja-Vazquez, Rafael ;   Seifert, Jennifer ;   Bak, M

Tags Neural interfaces – Neural stimulationNeural interfaces – Implantable systemsSensory neuroprostheses

Wireless stimulation of neural tissue could en- able many emerging neural prosthesis designs, and eliminate problems associated with...

Read More Download this Paper

Inode In-Vivo Testing for Selective Vagus Nerve Recording and Stimulation

Cota Monjaras, Oscar Fernando ;   Schloesser, Mario ;   Schiek, Michael ;   Stieglitz, Thomas ;   Gierthmuehlen, Mortimer ;   Plachta, Dennis T.T.

Tags Clinical neurophysiologyNeural interfaces – Neural stimulationNeural interfaces – Implantable systems

Hypertension is a wide spread disease and despite pharmacological treatment some patients cannot obtain any relief from medication. In...

Read More Download this Paper

Input Capacitance Compensated Neural Recording Amplifier

Chen, Changhao ;   Cui, Xutong ;   Pun, Sio Hang ;   Mak, Peng Un ;   Mak, Pui-In ;   Vai, Mang I. ;   Klug, Achim ;   Lei, Tim

Tags Neural interfaces – Microelectrode and fabrication technologies

Extracellular recording of a single neuron requires the use of a sharp electrode to measure action potentials originating from the target...

Read More Download this Paper

Iridium Oxide (IrOx) Serves as Adhesion Promoter for Conducting Polymers on Neural Microelectrodes

Boehler, Christian ;   Oberueber, Felix ;   Stieglitz, Thomas ;   Asplund, Maria

Tags Neural interfaces – Microelectrode and fabrication technologiesNeural interfaces – Neural microsystems and interface engineeringNeural interfaces – Biomaterials

Conducting polymers (CPs) as functional coatings on microelectrodes enable the realization of neural probes with superior electrical...

Read More Download this Paper

Large-Area, High-Density Arrays of Micro-Needles to Study Neural Connectivity in Acute Brain Slices

Gunning, Deborah E ;   Beggs, John ;   Dabrowski, Wladyslaw ;   Hottowy, Pawel ;   Kenney, Christopher ;   Sher, Alexander ;   Young, Douglas ;   Litke, Alan ;   Mathieson, Keith

Tags Neural interfaces – Microelectrode and fabrication technologies

This paper introduces a highly dense, large-area array of micro-needles developed specifically for in vitro, acute slice electrophysiology. The...

Read More Download this Paper

Light-Evoked Modulation of Neuronal Activity with Conjugated Polymers

Colombo, Elisabetta ;   Feyen, Paul ;   Endeman, Duco ;   Nova, Mattia ;   Antognazza, Maria Rosa ;   Lanzani, Guglielmo ;   Benfenati, Fabio ;   Ghezzi, Diego

Tags Neural interfaces – BiomaterialsNeural interfaces – Neural stimulation

Conductive polymers have been successfully employed to interface excitable cells through biocompatible probes and devices. We show here a...

Read More Download this Paper

Long-Term, High-Spatiotemporal Resolution Recording and Stimulation of Hippocampal Slice Cultures on Microelectrode Arrays

Gong, Wei ;   Radivojevic, Milos ;   Jäckel, David ;   Bakkum, Douglas ;   Hierlemann, Andreas

Tags Neural interfaces – Neural microsystems and interface engineeringNeural interfaces – Neural stimulation

Hippocampus is a brain region crucial for memory encoding and retrieval. Organotypic hippocampal slice cultures preserve the in vivo...

Read More Download this Paper

Metal to Parylene Adhesion Enhancement

Guo, Dongmei ;   Pei, Weihua ;   Chen, Hongda

Tags Neural interfaces – Microelectrode and fabrication technologiesNeural interfaces – Implantable systemsNeural interfaces – Neural microsystems and interface engineering

Parylene-C has been used extensively in neural interface devices as a conformal, biocompatible coating. It has also been widely used as a...

Read More Download this Paper

Micro Patterned Conductive Elastomers based on Silver Nanowire-PDMS

Stauffer, Flurin ;   Martinez, Vincent ;   Adagunodo, Mohammed ;   Voros, Janos ;   Larmagnac, Alexandre

Tags Neural interfaces – Microelectrode and fabrication technologiesNeural interfaces – Neural stimulationNeural interfaces – Biomaterials

Novel nanocomposites as silver nanowire (AgNW) networks embedded in PDMS are promising for use as highly conductive elastomers as well as in...

Read More Download this Paper

Microfabrication and Characterization of SU-8 based Neural Probes

Alves Malavazi, André Hernandes ;   Guevara, Jesus Arbey ;   Covolan, Roberto J. M. ;   Panepucci, Roberto Ricardo

Tags Neural interfaces – Microelectrode and fabrication technologiesNeural interfaces – Implantable systemsNeural interfaces – Neural microsystems and interface engineering

Neural probes are devices capable of establishing a connection between biological tissue and external circuitry, working as an interface that...

Read More Download this Paper

Model-Based Design of Control Modules for Neuromodulation Devices

Romero Ugalde, Hector Manuel ;   Ojeda, David ;   Le Rolle, Virginie ;   Rossel, Olivier ;   Bonnet, Jean-Luc ;   Karam, Nicole ;   Hagège, Albert ;   Mabo, Philippe ;   Carrault, Guy ;   Hernández, Alfredo I

Tags Neural interfaces – Neural stimulationNeural interfaces – Computational modeling and simulationNeural signal processing

Control systems design may be a difficult task when the system to be controlled is complex, poorly understood and with limited observability....

Read More Download this Paper

Modeling the Effects of Electrode Recessing on Electrochemical Safety in Cochlear Implant Electrodes

Sue, Andrian ;   Wong, Paul ;   Tran, Phillip ;   Li, Qing ;   Carter, Paul Michael

Tags Neural interfaces – Microelectrode and fabrication technologiesSensory neuroprostheses – AuditoryNeural interfaces – Computational modeling and simulation

Electrodes in neural prostheses may trigger stimulation-induced tissue damage if the magnitude of the stimulation exceeds safe levels....

Read More Download this Paper

Modulating Blood-Brain Barrier Healing Around Intracortical Electrode Implants

Falcone, Jessica ;   Yarabarla, Varun ;   Gresham, Brianna ;   Kretschmar, Robert ;   Paul, Shobha ;   Bellamkonda, Ravi

Tags Neural interfaces – Regeneration and tissue-electrode interfaceNeural interfaces – BiomaterialsNeural interfaces – Neural microsystems and interface engineering

Electrically interfacing with the brain is the next frontier. However, intracortical recording electrodes are greatly inhibiting by inflammation...

Read More Download this Paper

Nanostructured Diamond Microelectrode Arrays for Neural Recording and Stimulation

PIRET, Gaelle ;   Hébert, Clément ;   Mazellier, Jean-Paul ;   Rousseau, Lionel ;   Scorsone, Emmanuel ;   Cottance, Myline ;   Lissorgues, Gaelle ;   Heuschkel, Marc ;   Picaud, Serge ;   Bergonzo, Philippe ;   Yvert, Blaise

Tags Neural interfaces – Neural microsystems and interface engineeringNeural interfaces – BiomaterialsNeural interfaces – Neural stimulation

The development of stimulation implant and neuronal recording system currently needs highly stable and biocompatible microelectrode arrays...

Read More Download this Paper

Neural Activity Propagation by Electric Field in the Hippocampus in Vitro

Shivacharan, Rajat ;   Zhang, Mingming ;   Durand, Dominique

Tags Neural interfaces – Neural stimulationNeural signal processingNeurological disorders – Epilepsy

Synaptic transmission, gap junction, and ion diffusion are all well-studied modes of cell to cell communication. Electric field transmission is...

Read More Download this Paper

New Sectorized Implantable Microelectrode Fabrication, Packaging and Ageing for Neural Sensing and Stimulation

Bottausci, Frédéric ;   Baleras, François ;   Pudda, Catherine ;   Cochet, Martine ;   Chabrol, Claude ;   Sauter-Starace, Fabien ;   Oziat, Julie ;   Rovetta, Maelys ;   Icard, Beatrice ;   Guiraud, David ;   Divoux, Jean-Louis ;   Malbert, Charles-Henri ;   Henry, Christine ;   Maubert, Sandrine

Tags Neural interfaces – Implantable systemsNeural interfaces – Neural microsystems and interface engineering

This paper describes the fabrication and the packaging of a flexible parylene-based multi-contact electrode embedded in a silicone-based cuff....

Read More Download this Paper

Optimal Stimulus Waveforms for Eliciting a Spike: How Close is the Spike-Triggered Average?

Chang, Joshua ;   Paydarfar, David

Tags Neural interfaces – Computational modeling and simulationNeural interfaces – Neural stimulationNeural signal processing

Computing the average input stimulus preceding a spike, the spike-triggered average (STA), has been a powerful tool for discovering a...

Read More Download this Paper

PEDOT-Gelatin Coating Improves the Performance of Stimulating Microelectrodes for a Cortical Prosthesis

Brunton, Emma Kate ;   Rajan, Ramesh ;   Yan, Edwin ;   Gillespie-Jones, Katherine ;   Winther-Jensen, Bjorn

Tags Neural interfaces – Biomaterials

One of the major obstacles to developing high resolution visual cortical prostheses is finding an appropriate material for the stimulating...

Read More Download this Paper

Performance Optimization of the Wireless ECoG Recording Implant WIMAGINE® through Real-Time Lossless Data Compression

Foerster, Michael ;   Burdin, Florent ;   Dehaene, David ;   Lambert, Aurélien ;   Charvet, Guillaume

Tags Neural interfaces – Implantable systemsBrain-computer/machine interface – Robotics applicationsMotor neuroprostheses – Robotics

Read More Download this Paper

Phantom Model of Transcutaneous Electrical Stimulation with Kilohertz Signals

Medina, Leonel ;   Grill, Warren

Tags Neural interfaces – Neural stimulationNeural interfaces – Computational modeling and simulationNeuromuscular systems – Computational modeling and simulation

Transcutaneous electrical stimulation (TES) of nerve fibers may be optimized by overcoming the impedance of the skin using high-frequency...

Read More Download this Paper

Recording Properties of an Electrode Implanted in the Peripheral Nervous System: A Human Computational Model

Jehenne, Beryl ;   Raspopovic, Stanisa ;   Capogrosso, Marco ;   Arleo, Angelo ;   Micera, Silvestro

Tags Neural interfaces – Computational modeling and simulationNeural interfaces – Implantable systemsMotor neuroprostheses

Chronically implanted neural interfaces are aiming to create an intimate and long-term contact with neural cells. This would potentially allow...

Read More Download this Paper

Repairing Lesions via Kernel Adaptive Inverse Control in a Biomimetic Model of Sensorimotor Cortex

Li, Kan ;   Dura-Bernal, Salvador ;   Francis, Joseph Thachil ;   Lytton, William ;   Principe, Jose

Tags Neural signal processingNeural interfaces – Neural stimulationBrain physiology and modeling – Neuron modeling and simulation

In this paper we propose a kernel adaptive filtering (KAF) approach to repairing lesions via microstimulation in a biomimetic spiking neural...

Read More Download this Paper

Role of Major Burst Leaders in Modular Hippocampal Networks

Bisio, Marta ;   Pasquale, Valentina ;   Bosca, Alessandro ;   Berdondini, Luca ;   Chiappalone, Michela

Tags Brain physiology and modeling – Neural dynamics and computationBrain physiology and modeling – Neural circuitsNeural interfaces – Microelectrode and fabrication technologies

The development of in vitro neuronal models constituted by patterned networks is of significant interest in the neuroscientific community and...

Read More Download this Paper

Selective Stimulation of Peripheral Motor Nerve using a Flexible Split-Ring Electrode

Lee, Sanghoon ;   Sheshadri, Swathi ;   Xue, Ning ;   Tao, Sun ;   Chengkuo, Lee ;   Thakor, Nitish ;   Yen, Shih-Cheng ;   Delgado-Martínez, Ignacio

Tags Neural interfaces – Neural stimulationNeural interfaces – Microelectrode and fabrication technologiesMotor neuroprostheses – Prostheses

Selective fascicle stimulation is a requirement for the neuroprosthetic treatment of peripheral nerve injuries in order to achieve a proper...

Read More Download this Paper

Selective, Chronic Peripheral Nerve Recordings via Cuff Electrodes

Eggers, Thomas ;   Dweiri, Yazan ;   McCallum, Grant ;   Durand, Dominique

Tags Brain-computer/machine interfaceNeural signal processingMotor neuroprostheses

In recent years peripheral nerve interfaces have been explored as a possible source for generating control signals for prosthetic limbs. In...

Read More Download this Paper

Simulation Platform for Coupled Modeling of EM-Induced Neuronal Dynamics and Functionalized Anatomical Models

Neufeld, Esra ;   Vogiatzis, Ioannis ;   Iacono, Maria Ida ;   Akinnagbe, Esther ;   Angelone, Leonardo M. ;   Kainz, Wolfgang ;   Kuster, Niels

Tags Neural interfaces – Computational modeling and simulationNeuromuscular systems – Computational modeling and simulationTranscranial direct current and magnetic stimulation (TCDS/TMS)

A computational platform has been developed that is capable of simulating electromagnetic (EM) field interactions with neurons in complex...

Read More Download this Paper

Simultaneous Microelectrode Recording of Layered Structure of Cortex and Tonotopic Structure of Thalamus in the Auditory Pathway

Takahashi, Hirokazu ;   Shiramatsu, Tomoyo ;   Takahashi, Kazusa ;   Noda, Takahiro ;   Kanzaki, Ryohei ;   Nakahra, Haruka

Tags Neural interfaces – Microelectrode and fabrication technologiesSensory neuroprostheses – Auditory

Simultaneous characterization of layer-specific activation in the cortex and topographically organized activation in the thalamus brings...

Read More Download this Paper

Simultaneous Stimulation and Recording Validation with a High-Channel Count System

Barcikowski, Elliott ;   Hiatt, Scott ;   Wilder, Andrew M. ;   McDonnall, Daniel ;   Page, David ;   Wendelken, Suzanne ;   Clark, Gregory ;   Guillory, Kenneth Shane

Tags Neural interfaces – Neural stimulationNeural signal processing

We have developed a system for simultaneous stimulation and recording with neural electrodes, including electronic circuits and graphical...

Read More Download this Paper

Stimulation of Dorsal Root Ganglion Neurons by Infra-Red Laser Millisecond Pulses

Paris, Lambert ;   Charlot, Benoit ;   Dumas, Michel ;   Valmier, Jean ;   Bardin, Fabrice

Tags Neural interfaces – Neural stimulationSensory neuroprostheses – Somatosensory and vestibular

Neurostimulation by near infra-red laser pulses has therapeutic potential based on its ability to directly stimulate nerves without any genetic...

Read More Download this Paper

Stimulation of Small Diameter Myelinated and Unmyelinated Abdominal Vagal Neurons using High Frequency Pulses

Malbert, Charles-Henri ;   Divoux, Jean-Louis ;   Maciejasz, Pawel ;   PIcq, Chloé ;   Andreu, David ;   Guiraud, David

Tags Neural interfaces – Neural stimulationNeural interfaces – Implantable systemsNeuromuscular systems – Peripheral mechanisms

The voltage required to stimulate small diameter myelinated (Adelta fibres) and unmyelinated (C fibres) neurons consistently is so large that...

Read More Download this Paper

Synthetic Neuronal Circuits: Optically Active Semiconductor Microtubes as Remotely Accessible Sensors for Action Potentials

Koitmäe, Aune ;   Harberts, Jann ;   Loers, Gabriele ;   Müller, Manuel ;   Sonnenberg, David ;   Heyn, Christian ;   Hansen, Wolfgang ;   Blick, Robert H.

Tags Brain physiology and modeling – Neural circuitsNeural interfaces – BiomaterialsNeural interfaces – Neural microsystems and interface engineering

We present an advanced method of optical readout of action-potentials using optically active semiconductor microtubes (MT) as resonators...

Read More Download this Paper

The Effect of Triggered Endocardial Neuromodulation Decreasing Elevated Heart Rate

Pohl, Antje ;   Orschulik, Jakob ;   Idrissi, Akram ;   Lubba, Carl H. ;   Schauerte, Patrick ;   Hatam, Nima ;   Leonhardt, Steffen

Tags Neural interfaces – Neural stimulationNeural interfaces – Implantable systemsClinical neurophysiology

The heart rate is known to be an independent risk factor for higher overall mortality. Accordingly, there is a certain need for efficient...

Read More Download this Paper

Toward Complex Multipolar Selective Neural Stimulation

Guiho, Thomas ;   Rossel, Olivier ;   Souquet, Guillaume ;   Hernández, Alfredo I ;   Laporte, Laure ;   Azevedo, Christine ;   Andreu, David ;   Guiraud, David

Tags Neural interfaces – Neural stimulationNeural interfaces – Implantable systemsNeural interfaces – Neural microsystems and interface engineering

We introduce a new approach for the investigation of multipolar selective neural stimulation. We aim at comparing existing solutions from the...

Read More Download this Paper

Ultra-Low Power, Low Noise MAC Protocol Compliant Non-PLL based Wearable Transmitter for Dynamic Open Spectrum Sharing

Saraswat, Ruchir ;   Abbasi, Mohammad Usaid ;   Rodriguez-Villegas, Esther

Tags Neural interfaces – Sensors and body interfacesNeural interfaces – Neural microsystems and interface engineeringNeural interfaces – Implantable systems

The current paper proposes an ultra low power, low emission media access control (MAC) compliant frequency shift keying neural transmitter...

Read More Download this Paper

Visual Prosthesis based on Technique of Light Stimulus of the Optical Nerve

Ben Ayed, Hanen ;   Masmoudi, Jihen ;   Masmoudi, Mohamed

Tags Neural interfaces – Neural stimulationNeural signal processingSensory neuroprostheses – Visual

THE field of retinal prosthesis has been steadily developing over the last two decades [1],[2]. However, it still has some limitations such as...

Read More Download this Paper

µLED Probes for Site-Specific Optogenetic Neural Activation

Scharf, Robert ;   Sakata, Shuzo ;   Mathieson, Keith

Tags Neural interfaces – Neural microsystems and interface engineeringNeural signal processingNeural interfaces – Neural stimulation

Optogenetics has become a popular technique for studying neural circuits in recent years by allowing the optical control of genetically...

Read More Download this Paper