A Separated Carbon Nanotube Synapse

Lee, Rebecca K. ;   Zhang, Jialu ;   Parker, Alice ;   Zhou, Chongwu

Tags NanotechnologyBionanotechnology

A simple biomimetic synapse circuit has been fabricated using separated carbon nanotube transistors. Experimental results show that the...

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An Image Reconstruction Method Using Singular Value Decomposition for Magnetic Particle Imaging

Shimizu, Shota ;   Tsuchiya, Hiroki ;   takagi, tomoyuki ;   Hatsuda, Tomoki ;   Noguchi, Tomoaki ;   Ishihara, Yasutoshi

Tags DiagnosticsNanotechnologyMicrofluidics

Magnetic particle imaging is a medical imaging technology suitable for noninvasive diagnostics. However, the image resolution was degraded due...

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An Optically Transparent Micro-Ring Ultrasonic Detection Enables Isometric Multimodal Photoacoustic Microscopy

Dong, Biqin ;   Li, Hao ;   Zhang, Hao ;   Sun, Cheng

Tags NanotechnologyMicrofabricationDiagnostics

A cover-slip type transparent optical ultrasonic detector based on a polymeric micro-ring resonator was developed for achieving optical...

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Brain Stem Cell Interaction with Nanostructured Poly-Si/Pt Surfaces

Bérces, Zsófia ;   Horváth, Ágoston Csaba ;   Jády, Attila Gyula ;   Pongrácz, Anita ;   Madarász, Emília ;   Fekete, Zoltán

Tags NanotechnologyBionanotechnologyMicrofabrication

In this work, we investigate the biocompatibility of platinized poly-silicon surfaces with different nanoscale textures using NE-4C cell culture....

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Comparative Transfection of DNA by AuPAMAM Nanoparticles

Figueroa, Elizabeth ;   Yan, Stepehn ;   Chamberlain-Simon, Nicolette ;   Chen, Allen ;   Drezek, Rebekah

Tags NanotechnologyBionanotechnologyNanomedicine

In this study, we decipher differences in gene delivery by cationic gold-polyamidoamine nanoparticle (AuPAMAM) vectors in easy- and...

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Continuous Monitoring of Bacteria in Drinking Water

Svendsen, Winnie E ;   Bertelsen, Christian Vinther ;   Skands, Gustav ;   Dimaki, Maria ;   Clausen, Casper Hyttel

Tags NanotechnologyGlobal healthMicrofluidics

Real-time continuous monitoring of bacteria concentrations in drinking water is of great importance in drinking water management. The methods...

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Densification of Carbon Nanotubes via Uniaxial Shrinking

Kim, Joshua ;   Khine, Michelle

Tags Nanotechnology

Carbon nanotubes (CNTs) have become a widely studied nanoscale material ever since their discovery in 1991, and have been implemented in many...

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Development of Nanodiamond-Based Platform for Enhanced Cancer Stem Cell Therapy and Cancer Imaging

Wang, Xin ;   Moore, Laura ;   Ho, Dean ;   Chow, Edward

Tags NanomedicineBionanotechnologyNanotechnology

Cancers are often composed of heterogenous tumor cell populations. It is evident now that for many cancers, a specific subpopulation of...

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Encapusulation of Natural Synthesized Novel Nutraceutical Biomolecules

Kermasha, Selim ;   Aziz, Sarya

Tags NanotechnologyBionanotechnologyGlobal health

There has been growing evidence supporting the nutritional benefits of long-chain n-3-polyunsaturated fatty acids (ω-3-PUFAs), in...

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Flexible, Printable, and Biocompatible CNT-Based Conductive Ink for Fabrication of Supercapacitors and Biosensors

Shin, Su-Ryon ;   Farzad, Razieh ;   Monaharan, Vijian ;   Tamayol, Ali ;   Zhang, Yu Shrike ;   Duck jin, Kim ;   Annabi, Nasim ;   Comotto, Mattia ;   Akbari, Mohsen ;   Dokmeci, Mehmet R. ;   Khademhosseini, Ali

Tags NanotechnologyBionanotechnologyMicrofabrication

ABSTRACT--Multifunctional carbon nanotubes (CNTs) composite materials are currently of considerable interest in fabrication of flexible...

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Gold Nanoparticle-Mediated Delivery of Antigen and Adjuvant Improves Immune Response Resulting in Anti-Tumor Effects in Vivo

Mattos Almeida, Joao Paulo ;   Lin, Adam ;   Figueroa, Elizabeth ;   Reiser, Emily ;   Foster, Aaron ;   Drezek, Rebekah

Tags NanomedicineBionanotechnologyNanotechnology

Gold nanoparticles (AuNPs) facilitate the delivery of the peptide antigen ovalbumin (OVA) and the CpG adjuvant to improve the...

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Gold Nanoparticles for Targeted Oral Cancer Therapy In-Vivo Evaluation of Hepatotoxicity before Translation

Abdellatif, Omar ;   Saleh, Hazem ;   Salah, Taher ;   Elshazly, Mohamed Osama ;   Khalil, Adel ;   Raafat, Alaa

Tags NanomedicineBionanotechnologyNanotechnology

Gold nanoparticles (GNPs) possess promising potential for curing cancer via photothermal therapy. However, their safety must be addressed...

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Graphene-Coated Textile Sensors for Intelligent Medical Garments

Elboshra, Tamador ;   Abdul Samad, Yarjan ;   Li, Yuanqing ;   Liao, Kin ;   Yapici, Murat Kaya

Tags NanotechnologyPoint-of-careGlobal health

This paper reports, for the first time, graphene-coated textile electrodes for biosignal acquisition which can be scaled-up to realize wearable...

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In Situ iPSC Reprogramming by Non-Viral Chitosan-Based Assembly

Mikhailov, Andrey ;   Saotome, Kousaku ;   Matsushita, Akira ;   Sankai, Yoshiyuki

Tags NanotechnologyStem cellsRegenerative medicine

Here we are demonstrating the assembly from the set of chitosan-based functional materials with defined nano- and macro-properties into...

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Lipid Multilayer Nanostructures on Surfaces as Bioinspired Compartments

Lenhert, Steven

Tags BionanotechnologyNanotechnologyNanomedicine

Lipid bilayer membranes form the basis of compartments such as cells and organelles in biology. Fabrication of lipid multilayer nanostructures...

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Low-Dosages of Zeolite 13X Produce a Bimodal Effect on Breast Cancer Cells: Geno-Oxidative Damage and Reduction of Lipid Peroxidation

Malara, Natalia, Maria ;   Tiriolo, Raffaele ;   Trunzo, Valentina ;   Pullano, Salvatore A. ;   Elisabetta, Dattola ;   Paola, Failla ;   di Fabrizio, Enzo ;   Mollace, Vincenzo ;   Fiorillo, Antonino S.

Tags DiagnosticsNanotechnology

Zeolite is a nanoporous material possessing excellent properties for application in medical and biological engineering. The effects of low...

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Magnetic Guidance of Temozolomide-Containing Particles through Brain Tissue

Mair, Lamar ;   Weinberg, Irving ;   Nacev, Alek ;   Stepanov, Pavel ;   Urdaneta, Mario ;   Hilaman, Ryan ;   Himmelfarb, Stephanie ;   Diaz-Caballero, Elena ;   Rigla, Juan Pablo ;   Kulkarni, Sandip ;   Shapiro, Benjamin

Tags NanomedicineNanotechnologyMicrofabrication

Temozolomide (TMZ) is an FDA approved drug for treatment of brain tumors. Encapsulation of this drug in a magnetic nanoparticle carrier has...

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Maximizing the Intracellular Delivery of Spherical Nucleic Acids by Engineering Oligonucleotide Sequence

Narayan, Suguna ;   Choi, Chung Hang J ;   Hao, Liangliang ;   Calabrese, Colin ;   Mirkin, Chad

Tags BionanotechnologyNanotechnologyNanomedicine

Spherical nucleic acids (SNAs), consisting of densely packed, highly oriented oligonucleotides attached to the surface of nanoparticles, are...

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Multi-Scale Topographical Patterned Substrates for Promoting Differentiation of Human Neural Stem Cells

Yang, Kisuk ;   Jung, Hyunjung ;   Lee, Hak-Rae ;   Bang, Joona ;   Im, Sung Gap ;   Cho, Seung-Woo

Tags NanotechnologyStem cellsTissue engineering

Self-renewal and differentiation of human neural stem cells (hNSCs) can be controlled by surface topography of culture substrates. In this...

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Multiplexed SERS for Rare Cell Detection in Flow

Hoonejani, Mehran ;   Pallaoro, Alessia ;   Braun, Gary ;   Moskovits, Martin ;   Meinhart, Carl

Tags NanotechnologyMicrofluidicsDiagnostics

The reliable and fast identification of different types of cells is of utmost importance in several biomedical applications. The detection of...

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Nanoscale Neuromorphic Circuit to Model DemylinationRemyelination

Yue, Kun ;   Parker, Alice

Tags NanotechnologyBionanotechnologyNanomedicine

We demonstrated Neuromorphic circuit models for Demyelinated and Remyelinated axons. Nanoscale devices including nanoresistors and...

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Needle Microelectrodes for Electromyography Recording from Zebrafish Larvae

Cho, Sung-Joon ;   Nam, Tae-Seung ;   Choi, Seok-Yong ;   Kim, Myoung-Kyu ;   Kim, Sohee

Tags MicrofabricationBionanotechnologyNanotechnology

Electromyography (EMG) is the most effective tool in diagnosing muscular diseases, and it is an essential tool in developing treatment agents...

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Selective Cell Adhesion to Surface Nanotopography

Liang, Elena ;   Dickson, Mary Nora ;   Yee, Albert

Tags Nanotechnology

In this work, we present the use of nanotopography as a method to control cell adhesion on materials surfaces without chemical surfaces...

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Sirna-Based Spherical Nucleic Acid Nanoparticle Conjugates Increase the Rate of Wound Healing in Subjects with Type 2 Diabetes

Randeria, Pratik ;   Paller, Amy S. ;   Mirkin, Chad

Tags BionanotechnologyNanomedicineNanotechnology

Diabetic patients often suffer from impaired wound healing, which can develop into non-healing diabetic ulcers, facilitate bacterial infections,...

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Sol-Gel Derived Silica Structures for Enhanced Fluorescence Sensing

Lin, Sophia ;   Khine, Michelle

Tags DiagnosticsMicrofabricationNanotechnology

Efforts to improve the detection sensitivity and signal-to-noise ratios (SNRs) of low-abundance target molecules have resulted in engineered...

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Stickyflares: A Platform for the Quantification and Spatio-Temporal Tracking of RNA in Live Cells

Briley, William ;   Mirkin, Chad

Tags BionanotechnologyNanotechnologyNanomedicine

We report a novel gold nanoparticle-DNA conjugate, termed the Stickyflare, which provides a platform for facile quantification of relative RNA...

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Targeted Magnetic Resonance Imaging through Nanodiamonds

Moore, Laura ;   Towsend, Taryn R. ;   Meade, Thomas J. ;   Ho, Dean

Tags NanomedicineNanotechnologyDiagnostics

Steroid hormone receptors play a key role in the prognosis and treatment of a variety of cancers including breast, ovarian and prostate....

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Temperature Dependence of Scanning Angle Frequency Response of Electrostatic Comb-Actuated Micro-Scanner

Ikeda, Kentaro ;   Okazaki, Koji ;   Ishikawa, Noriaki ;   Sawada, Renshi

Tags BioMEMSNanotechnology

We have investigated the temperature dependence of scanning angle frequency response of the electrostatic comb-actuated micro-scanner...

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The Axonal Spatial-Temporal Reactive Assembly (astra)

Morgera, Salvatore Domenic

Tags NanotechnologyMicrofabricationNanomedicine

An emerging intersection of the neuroengineering of nerve fiber (axon) tracts/bundles and communications networks is described. At the...

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Three-Dimensional Textured Graphene Bioelectronics

Wang, Michael Cai ;   Choi, Jonghyun ;   Yong, Keong ;   Ashraf, Ali ;   Nam, SungWoo

Tags NanotechnologyBionanotechnologyDiagnostics

Superb electromechanical properties of graphene, where large elastic deformation is achievable without significant perturbation of electrical...

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Top-Down Designing and Fabrication of Metal Nanostructures for Plasmonics-Assisted Biomedical Sensing Applications

Chang, Chieh-feng ;   Walavalkar, Sameer ;   Marin, Brandon ;   Scherer, Axel

Tags NanotechnologyBionanotechnologyNanomedicine

Traditionally plasmonics was approached with bottom-up synthesis or time-consuming techniques like focused ion beam (FIB). We report an...

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Towards a Scalable Biomimetic Antibacterial Coating

Dickson, Mary Nora ;   Liang, Elena ;   Vollereaux, Nicolas ;   Yee, Albert

Tags NanotechnologyBionanotechnologyGlobal health

This work presents proof of concept that a biomimetic nanostructured surface can kill bacteria upon adhesion, without the use of chemical...

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