Design and Simulation of Device for Breach Microfluidics Membrane for the Detection of Hiv (aids)

Lagos, Jose ;   Leguizamon, Ana ;   Quiroga, Daniel

This article present a model of diagnostic device that using chemical reagents and microfluidics as particle separation is developed to diagnose the virus acquired immunodeficiency (HIV or AIDS), the device allows you to isolate leukocytes and apply these a reagent measures the presence or on the virus. The design uses as tools, SolidWorks, Autodesk Simulation and CFD simulation, based on these tests, the membranes rupture and separation of components, enabling the chemical reaction at the particles and the virus detection. Based on the choice of particle analysis, validating the performance of the fluid held in the filter stage, represented by 5 lines of flux, showing movement of 5 the particles, having the same diameter, here three tests were performed by varying the diameter of the particles, as well: first, less than 10μm particle diameter (5 μm), second, equal to the particle diameter of 10μm and finally a 10μm greater diameter (15μm) particle. The results show that with the diameter of 5 μm, the particles travel smoothly and the filter may reach the next stage. Similarly, for particles of diameter 10μm, normal blood flow in the filtering stage is presented, however it can be observed an obstruction, from the center of the trajectory, and finally, the particle simulation of 15 μm diameter shows that only two of the particles are affected by the filter and trapped into the paths to ribbons, we can get an idea of the change present