Microfluidic Based Detection of HepA, HepB, and HepC Using Fluorescent Silver Nanocluster Probes (AgNC-DNA)

Del Bonis-O'Donnell, Jackson Travis ;   Fygenson, Deborah ;   Pennathur, Sumita

Fluorescent silver nanocluster DNA probes (AgNC-DNA) are a new class of fluorophores with emerging applications in biology and medicine. Using these probes combined with microfluidic capillary electrophoresis (mCE), we demonstrate a novel approach to detect and identify DNA sequences from HepA, HepB and HepC viruses simultaneously from a single sample.