Low Percolation Threshold Conductive POSS-PCL/Graphene Nanocomposite Polymer; Application for Nerve Regeneration

Nezakati, Toktam ;   Seifalian, Alexander

A low percolation threshold electrically conductive polymer using polyhedral oligomeric silsesquioxane (POSS) nanocage incorporated into a modified poly [caprolactone based urea-urethane] (PCL)/graphene hybrid nanocomposite is described. Multilayer graphene flakes (8 nm) were homogeneously dispersed into POSS-PCL at 0.08, 0.4, 0.8, 1.6, and 4.0 wt. % concentrations. The impedance spectroscopy of 0.08 wt. % and higher concentration of graphene in POSS-PCL represented major improvement in conductivity over pristine POSS-PCL. The percolation threshold occurred at 0.4 wt. % graphene concentration, and at 4.0 wt. % the electrical conductivity showed better than 10-2 Scm-1. This paper also addresses the investigation growth of neural Schwann Cells (SCs) on POSS-PCL/Graphene as a substrate for the repair of damaged nervous system.