Perfusion-Based Three Dimensional (3D) Tissue Engineering Platform with Integrated Bioimpedance Sensing

Muhammad, Haseena Bashir ;   Canali, Chiara ;   Heiskanen, Arto ;   Hemmingsen, Mette ;   Wolff, Anders ;   Dufva, Martin ;   Emnéus, Jenny

We present an 8-channel bioreactor array with integrated bioimpedance sensors, which enables perfusion culture of cells seeded onto porous 3D scaffolds. Results show the capability of the system for monitoring cell proliferation within the scaffolds through a culture period of 19 days.