Physical Phenotyping of Single-Cells for Biomedicine

Di Carlo, Dino

Physical properties of cells can provide integrative and quantitative information about various disease states. I will discuss a range of microtechnologies we have developed to assay the physical properties of cells – size, deformability, adhesiveness, and contractility, in a high-throughput a quantitative manner. I will introduce applications where we are using these approaches as diagnostic and drug screening tools.