Investigating the Role of M2a Polarized Macrophages on Carcinoma Cell Aggregates Dispersion in a 3D Microfluidic Device

Adriani, Giulia ;   Bai, Jing ;   Dang, Truong-Minh ;   Tu, Ting-Yuan ;   Wong, Siew-Cheng ;   Thiery, Jean Paul ;   Kamm, Roger D.

In this study, we present a microfluidic platform to investigate macrophage-cancer cell aggregates interactions. In particular, we investigate the contact-induced carcinoma aggregate dispersion by polarized M2a macrophages.