Multimodal Size-Based Microfluidic Sorters

Papautsky, Ian ;   Wang, Xiao

Microfluidic sorting of cells has attracted much interest in recent years. However, most microfluidic devices are only capable of bimodal separation with a single cutoff diameter and a well-defined size difference. Here, we use inertial microfluidics to demonstrate continuous multimodal sorting of cells with high resolution and high tunability of the separation cutoff diameters. We envision use of such devices in a wide range of applications involving more complex cell mixture, from cell biology to cancer theranostics.