Development of a Portable, Automated, and Multiplexed Diagnostics Platform Using Photonic Crystal Enhanced Fluorescence Assays

Cunningham, Brian

Photonic crystal enhanced fluorescence (PCEF) has been demonstrated as an effective approach for magnifying the output of any surface-based fluorescence assay by several orders of magnitude. The talk will describe recent efforts to transition PCEF technology towards clinical diagnostics applications through integration with microfluidics for assay automation, a portable laser scanning instrument, and assays for multiplexed detection of allergens and cancer biomarkers in serum.