A Medium Throughput Device to Study the Effects of Combinations of Surface Strains and Fluid-Flow Shear Stresses on Cells

Sinha, Ravi ;   Le Gac, Séverine ;   Verdonschot, Nico ;   van den Berg, Albert ;   Koopman, Bart ;   Rouwkema, Jeroen

Tags Regenerative medicineLab-on-ChipMicrofluidics

We report a 96-well-plate-sized device to screen for the effects on cells of all combinations of five equibiaxial surface strains (2-20%...

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A Microfluidic Platform to Study and Modulate the Blood-Brain Barrier

van der Helm, Marieke Willemijn ;   Frimat, Jean-Philippe ;   Odijk, Mathieu ;   van den Berg, Albert ;   Segerink, Loes Irene

Tags Lab-on-ChipBioMEMSMicrofluidics

A simple yet predictive model of the blood-brain barrier (BBB) is required to help drug development and improve the understanding of the...

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Microfluidic Single Sperm Entrapment and Analysis

de Wagenaar, Bjorn ;   Berendsen, Jorien ;   Huisintveld, Nik ;   Olthuis, Wouter ;   van den Berg, Albert ;   Segerink, Loes Irene

Tags MicrofluidicsBionanotechnologyDiagnostics

This abstract describes the hydrodynamic trapping of single spermatozoa in a microfluidic platform, allowing the investigation of sperm...

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