An iPS-derived, Vascularized Cardiac Tissue as an in vitro Drug Screening Platform

Kurokawa, Yosuke ;   Tran, David ;   Moya, Monica ;   Sobrino, Agua, Agua ;   Alonzo, Luis ;   Tu, Christina ;   Lock, Leslie ;   Hughes, Christopher ;   Conklin, Bruce ;   George, Steven

Tags Tissue engineeringStem cellsMicrofluidics

Drug attrition due to cardiac toxicity is prevalent, and a better preclinical screening tool is required in order to solve this issue. Here we...

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Electrical Pacing of 3D Ips-Derived Cardiomyocytes and Endothelial Cells in a Microfluidic Device

Lam, Sandra ;   Simon, Melinda ;   Tran, David ;   Alonzo, Luis ;   Flohn, Nicholas ;   Lee, Abraham ;   George, Steven

Tags MicrofluidicsStem cellsTissue engineering

Tissue engineering models of human tissue have frequently utilized microfabricated systems to accurately and consistently provide simultaneous...

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