Controlling Cell Migration and Adhesion into a Scaffold by External Electric Currents

Jaatinen, Leena ;   Hyttinen, Jari ;   Voros, Janos

Tags Engineered matrices for ES and stem cell maintenanceCell spreading and adhesionCell polarity and spatial patterning

Fabrication of more complex tissue-engineered structures, resembling the tissues and organs in vivo requires combining more than one cell...

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Microengineered Embryonic Stem Cells Niche to Induce Neural Differentiation

Joshi, Ramila ;   Tavana, Hossein

Tags Stem cell nicheControlling embryonic cell differentiation

A major challenge in therapeutic use of embryonic stem cells (ESCs) for treating neurodegenerative diseases is creating a niche in vitro for...

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Mimicking Biophysical Stimuli within Bone Tumor Microenvironment

Marturano, Alessandro ;   Yeager, Keith ;   Bach, Daniel ;   Villasante, Aranzazu ;   Cimetta, Elisa ;   Vunjak-Novakovic, Gordana

Tags Bioreactor based translational tissue engineeringMechanical stimuli and mechanotransductionTranslational models

In vivo, cells reside in a complex environment regulating their fate and function. Most of this complexity is lacking in standard in vitro models,...

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On-Line Tracking of Living Cell Subjected to Cyclic Stretch

Huang, Wenjing ;   Ahmad, Belal ;   Kawahara, Tomohiro

Tags Mechanical stimuli and mechanotransductionCell motility and force transduction

We propose a novel system for the observation of living cell exposed to cyclic stretch under dynamic conditions. The developed system is...

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