A 3-D Admittance-Level Computational Model of a Rat Hippocampus for Improving Prosthetic Design

Gilbert, Andrew ;   Loizos, Kyle ;   RamRakhyani, Anil ;   Hendrickson, Phillip ;   Lazzi, Gianluca ;   Berger, Theodore

Tags Multiscale modelingMedical device modeling

Hippocampal prosthetic devices have been developed to bridge the gap between functioning portions of the hippocampus, in order to restore...

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A 3D-Continuum Bidomain Model of Retinal Electrical Stimulation using an Anatomically Detailed Mesh

Shalbaf, Farzaneh ;   Du, Peng ;   Lovell, Nigel H. ;   Dokos, Socrates ;   Vaghefi, Ehsan

Tags Biomechanics modelingMultiscale modelingCell modeling

A continuum bidomain model of sub-retinal electrical stimulation on an anatomically detailed mesh of retina is presented. The underlying...

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A Model of Electrical Stimulation of a Retinal Cell Population using a Multi-Electrode Array

Al Abed, Amr ;   Lovell, Nigel H. ;   Suaning, Gregg ;   Dokos, Socrates

Tags Medical device modelingPhysiome modelingIonic modeling

A computational modelling approach is employed to investigate the response of a population of retinal ganglion cells (RGCs) to external...

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Analysis of Bipolar External Excitation of Spherical Tissue by Spatially Opposed Current Source and Sink Points

Schwartz, Benjamin ;   Sadleir, Rosalind

Tags Physiological systemsIonic modelingInverse problems in biology

The recently increasing role in medical imaging that electrophysiology plays has spurned the need for its quantitative analysis at all scales –...

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External Current Application in a Bidomain Model of Active Neural Tissue

Keim, Steven ;   Fu, Fanrui ;   Sadleir, Rosalind

Tags Ionic modelingInverse problems in biologyMultiscale modeling

The formal treatment of tissue as two coupled continua is referred to as a bidomain model. Bidomain models have recently been used to...

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Reactive Near Field Electromagnetic Axonal Communication Channels and Their Role in Neurodegenerative Diseases

Morgera, Salvatore Domenic

Tags Advances in theory of biological networksAlgorithms and techniques for systems modelingClinical applications of biological networks

Research focus is on the micron-scale subsystem of the human nervous system known as the axon, or nerve fibre. In studying what has been...

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