Affordable Techniques for Fabricating Large Array of Functional Nanowires: From DNA to Micellar Systems

Glazer, Piotr Jakub ;   Boukany, Pouyan

Tags Directed assemblyBiofabricationSelf-assembled biomaterials

Large arrays of aligned DNA and polymeric nanowires ranging from 20 to 100 nm in diameter are fabricated by de-wetting of patterned...

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An Automated Microphysiological Assay for Toxicity Evaluation

Eggert, Sebastian ;   Alexander, Frank ;   Wiest, Joachim

Tags Instrumentation of cell-substrate and cell-cell interactionsChemical and electrochemical sensorsSensors for evaluation of drug activity

Screening a newly developed drug, food additive or cosmetic ingredient for toxicity is a critical preliminary step before it can move forward...

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High-Speed Event Detector for Embedded Nanopore Bio-Systems

Huang, Yiyun ;   Magierowski, Sebastian ;   Ghafar-Zadeh, Ebrahim ;   Wang, Chengjie

Tags DNA sensorsChemical and electrochemical sensors

Biological measurements of microscopic phenomena often deal with discrete-event signals. The ability to automatically carry out such...

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Low-Power Adaptive Spike Detector based on a Sigma-Delta Control Loop

Gagnon-Turcotte, Gabriel ;   Sawan, Mohamad ;   Gosselin, Benoit

Tags Instrumentation of cell-substrate and cell-cell interactionsSensors for evaluation of drug activityBio-MEMS and cell mechanics

This paper presents a resources-optimized digital action potential (AP) detector featuring an adaptive threshold based on a new Sigma-delta...

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Microfluidic Platform for Neurotransmitter Sensing based on Cyclic Voltammetry and Dielectrophoresis for in Vitro Experiments

Greener, Jesse ;   Miled, Amine ;   Mathault, Jessy

Tags GalvanotaxisElectromagnetic field effects and cell membrane

This paper presents new neuro-interface in order to simultaneously measure and locally modulate neurotransmitter (NT) concentration in a...

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Robotic Printing and Drug Testing of 384-Well Tumor Spheroids

Ham, Stephanie ;   Thakuri, Pradip ;   Tavana, Hossein

Tags Micro-/nano-fabrication in tissue engineeringBiofabricationSelf-assembled biomaterials

A major impediment to anti-cancer drug development is the lack of a reliable and inexpensive tumor model to test the efficacy of candidate...

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