A Strain-Dependent Diffusivity Model to Study the Nuclear Import of Mechanobiological Transcription Factors

Nava, Michele ;   Fedele, Roberto ;   Raimondi, Manuela Teresa

Tags Modeling and simulation in musculoskeletal biomechanicsMultiscale biomechanics

Nuclear spreading plays a crucial role in stem cell fate determination. In previous works, we reported evidence of multipotency maintenance of...

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Modulation of Cellular Responses: The Two-Photon Polymerization Approach in the Control of the Physical Micro/Nanoenvironment

Marino, Attilio ;   Filippeschi, Carlo ;   Mattoli, Virgilio ;   Mazzolai, Barbara ;   Ciofani, Gianni

Tags New technologies and methodologies in medical robotics and biomechanicsMicro-and nano-biorobotics

Cells and tissues are extremely sensitive to their physico-chemical surroundings: in regenerative medicine, as an example, the maintenance of...

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Real-Time Deformability Cytometry as a Label-Free Indicator of Cell Function

Otto, Oliver ;   Rosendahl, Philipp ;   Golfier, Stefan ;   Mietke, Alexander ;   Herbig, Maik ;   Jacobi, Angela ;   Toepfner, Nicole ;   Herold, Christoph ;   Klaue, Daniel ;   Girardo, Salvatore ;   Winzi, Maria ;   Fischer-Friedrich, Elisabeth ;   Guck, Jochen

Tags New technologies and methodologies in medical robotics and biomechanics

The mechanical properties of cells are known to be a label-free, inherent marker of biological function in health and disease. Wide-spread...

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Theory and Application of Arterial Tissue In-Host Remodelling

Zunino, Paolo

Tags Modeling and simulation in biomechanics : prostheticsApplied tissue and organ models and motion analysisMultiscale biomechanics

A central therapeutic goal in many applications of modern Biomedicine is the reconstruction of the diseased arterial sections via robust and...

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Tissue Motion Due to Needle Deflection

Leibinger, Alexander ;   Burrows, Christopher ;   Oldfield, Matthew ;   Rodriguez y Baena, Ferdinando

Tags Modeling in bioroboticsBiomimetic roboticsNew technologies and methodologies in medical robotics and biomechanics

Various concepts of steerable needles have been developed in order to reduce placement errors during insertions and to enable complex...

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Using Microfluidics to Investigate Tumor Cell Extravasation and T-Cell Immunotherapies

Pavesi, Andrea ;   Tanoto, Tan Anthony ;   Chen, Michelle ;   Adriani, Giulia ;   Antonio, Bertoletti ;   Kamm, Roger D.

Tags Micro-and nano-biorobotics

Understanding the mechanism of tumor cell extravasation, cell migration and the role of the immunosystem is crucial in creating targeted and...

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