A Gap Junction-Based Cardiac Electromechanics Model

Ahmad Bakir, Azam ;   Dokos, Socrates

Tags Biomechanics modelingIonic modelingPhysiological systems

Action potential propagation in cardiac tissue is mainly governed by highly resistive gap junctions, which causes the tissue to behave as a...

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Autonomic Nervous System Regulation of the Sinoatrial Cell Depolarization Rate: Unifying Computational Models

Castellanos, Norma Pilar ;   Godinez, Rafael

Tags Cell modelingModeling of biomolecular system dynamics

In the last years different computational models have been proposed to simulate the sinoatrial node cell (SANC) action potential. Also, there...

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From the Purkinje Fibres to the Ventricle: One Dimensional Computer Simulation for the Healthy and Failing Heart

Li, Jue ;   Logantha, Sunil Jit ;   Yanni, Joseph ;   Cai, Xue ;   Dobrzynski, Halina ;   Hart, George ;   Boyett, Mark Richard

Tags Physiological systems

This study used one-dimensional computer simulation to investigate the influence of heart failure on action potential conduction through the...

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In Silico Modelling and Analysis of the Electrical and Mechanical Properties of in Vitro Cardiac Cultures with Different Fiber Architectures

Del Bianco, Fabrizio ;   Colli Franzone, Piero ;   Scacchi, Simone ;   Fassina, Lorenzo

Tags Multiscale modelingBiomechanics modelingIonic modeling

Today, in vitro cardiac cultures are widely exploited to investigate several aspects of the electromechanical behavior of the cardiac tissue....

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Modelling the Effect of Thickness on the Electromechanical Properties of in Vitro Cardiac Cultures: A Simulation Study

Del Bianco, Fabrizio ;   Colli Franzone, Piero ;   Scacchi, Simone ;   Fassina, Lorenzo

Tags Multiscale modelingBiomechanics modelingIonic modeling

Nowadays, in vitro cardiac cultures offer a valid tool to study the bioelectrical activity and the biomechanics of the heart tissue. Modelling...

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Role of Atrium in Automaticity of the Sinus Node

Zhang, Hong

Tags Physiological systems

As the electrical source of hearts, sino-atrial node cells (SANCs) play significant roles in rhythmic firings. Due to the complex structure and...

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