<i>In silico</i> Kinetic Model of iNOS Expression in Macrophages

Salim, Taha ;   May, Elebeoba

Tags Modeling of biomolecular system pathwaysNetwork modelingBiomedical data-driven modeling

Macrophages are a key component in the host innate response and are major contributors to the proinflammatory response against pathogens....

Read More Download this Paper

A Comparison between Direct and Indirect Measurements of Neurotransmitter Vesicle Release Dynamics: A Computational Study

Hu, Eric ;   Bouteiller, Jean-Marie Charles ;   Huang, Mike ;   Song, Dong ;   Berger, Theodore

Tags Modeling of biomolecular system dynamics

Presynaptic vesicular release of neurotransmitters is a stochastic process involving complex mechanisms triggered by an elevation of calcium...

Read More Download this Paper

Homo-Oligomerization of Transmembrane ? -Domain of Integrin

Shamloo, Amir ;   Nikbin, Ehsan ;   Mehboudi, Nastaran ;   Damirchi, Behzad

Tags Modeling of biomolecular system dynamicsBiomechanics modelingStructural bioinformatics

Integrins contribute to the formation of focal adhesions. Therefore, simulation of integrin interactions can be helpful in clarifying the...

Read More Download this Paper

Pathway-Based Expression Profile for Breast Cancer Diagnoses

Cava, Claudia ;   Bertoli, Gloria ;   Castiglioni, Isabella

Tags Modeling of biomolecular system pathways

Microarray experiments have made possible to identify breast cancer marker gene signatures. However, gene expression-based signatures...

Read More Download this Paper

Roles of Regulated Internalization in the Polarization of Cell Surface Receptors

Tian, Wei ;   Cao, Youfang ;   Ismael, Amber ;   Stone, David ;   Liang, Jie

Tags Modeling of biomolecular system dynamicsNetwork modeling

Cell polarization, the generation of cellular asymmetries, is a fundamental biological process. Polarity of different molecules can be generated...

Read More Download this Paper

Synthesis of Optimal Control of Complex Biological Pathways Enabled by Global Sensitivity Analysis

Salighehdar, Amin ;   Ganesan, Narayan

Tags Modeling of biomolecular system dynamicsModeling of biomolecular system pathwaysModeling of gene/epigene regulatory networks

This paper has been removed from the conference proceedings.

Read More Download this Paper