A Hybrid Dynamic Bayesian Network Approach for Modelling Temporal Associations of Gene Expressions for Hypertension Diagnosis

Akutekwe, Arinze ;   Seker, Huseyin

Tags Mining clinical dataBiomedical data-driven modelingMedical decision making

Computational and machine learning techniques have been applied in identifying biomarkers and constructing predictive models for diagnosis of...

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Construction of Protein Dendrograms Based on Amino Acid Indices and Discrete Fourier Transform

Chrysostomou, Charalambos ;   Seker, Huseyin

Tags Algorithms and computational tools for proteomicsStructured data visualization

From the literature, existing methods use pairwise percent identity to identify the percentage of similarity between two protein sequences, in...

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Hybrid Imbalanced Data Classifier Models for Computational Discovery of Antibiotic Drug Targets

Kocyigit, Yucel ;   Seker, Huseyin

Tags Algorithms and techniques for systems modelingParameter estimationStructural bioinformatics

Identification of drug candidates is an important but also difficult process. Given drug resistance bacteria that we face, this process has...

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Prediction of Protein Allergenicity Based on Signal-Processing Bioinformatics Approach

Chrysostomou, Charalambos ;   Seker, Huseyin

Tags Algorithms and computational tools for proteomics

Current bioinformatics tools accomplish high accuracies in classifying allergenic protein sequences with high homology and generally perform...

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Symmetrical Directional Dual-Tree Complex Wavelet Packet Transform

Serbes, Gorkem ;   Gulcur, Halil Ozcan ;   Aydin, Nizamettin

Tags Medical decision making

In this study, a symmetrical directional complex discrete wavelet packet transform, which can be applied directly to the quadrature format...

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