Can Cell Mechanics Be Described by Elastic Modulus in AFM Indentation Experiments

Sokolov, Igor ;   Dokukin, Maxim

Tags Bio-nano technologyMechanical sensors and systems

Here we present our investigation of the question if cells, being highly heterogeneous objects, can be described with the elastic modulus in a...

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Comparison of Nano and Micro Scale Mechanics of Murine Articular Cartilage

Azadi, Mojtaba ;   tavakoli nia, Hadi ;   Ortiz, Christine ;   Grodzinsky, Alan

Tags Bio-nano technologyMicro- and nano-technology

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Fluctuations in Cellular Forces: Noise or Signal?

Knoll, Samantha ;   Saif, M Taher A

Tags Mechanical sensors and systemsMicrofluidic techniques, methods and systems

Cells sense their mechanical micro-environment by generating contractile forces. Conventionally these forces are expected to reach a steady...

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Mechanoregulation of Stem Cell Fates Using Density-Controlled Nanotopographic Cues

Kim, Deok-Ho

Tags Bio-nano technology

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Probing the Dynamics of Actomyosin Contractility in Vitro by Modulating Myosin Activity with Light

Murrell, Michael ;   Linsmeier, Ian

Tags Micro- and nano-technology

Myosin II-induced mechanical stresses within the F-actin cortex are responsible for mediating cortical flows and cell shape changes during...

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Probing the T Cell Mechanosensor at the Single Molecule and Single Cell Levels

Lang, Matthew

Tags Bio-nano technologyMechanical sensors and systemsBiological sensors and systems

Mechanosensor action of the TCR-pMHC linkage is probed in both single molecule and single cell assays. Bond lifetimes as a function of load are...

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Single Cell Gene Expression Analysis for Probing Collective Cell Migration

Wong, Pak Kin

Tags Bio-nano technology

Collective cell migration plays important roles in key biological processes, such as regenerative medicine and cancer metastasis. However,...

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