A Multi-Tissue Segmentation of the Human Head for Detailed Computational Models

Hannula, Markus ;   Narra, Nathaniel ;   Onnela, Niina Maritta ;   Dastidar, Prasun ;   Hyttinen, Jari

Tags Biomedical data-driven modelingMultiscale modeling

This paper describes the creation of an anatomically detailed high resolution model of the human head based on the Visible Human Female data...

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Altered Small-World Anatomical Networks in Apolipoprotein-E4 (ApoE4) Carriers Using MRI

Goryawala, Mohammed ;   Zhou, Qi ;   Duara, Ranjan ;   Loewenstein, David ;   Cabrerizo, Mercedes ;   Barker, Warren ;   Adjouadi, Malek

Tags Biomedical data-driven modelingStructural bioinformaticsModeling of gene/epigene regulatory networks

Apolipoprotein E (ApoE) gene and primarily its allele e4 have been identified as a risk factor for Alzheimer's disease (AD). The prevalence of...

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Development of a Diffusion-Based Mathematical Model for Predicting Chemotherapy Effects

Wang, Zhihui ;   Kerketta, Romica ;   Chuang, Yao-Li ;   Cristini, Vittorio

Tags Biomedical data-driven modelingAlgorithms and techniques for systems modelingPK/PD

Mathematical modeling of drug transport can complement current experimental and clinical investigations to understand drug resistance...

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Effects of Genetic Variation on the Dynamics of Neurodegeneration in Alzheimer's Disease

Printy, Blake ;   Verma, Nishant ;   Cowperthwaite, Matthew ;   Markey, Mia

Tags Biomedical data-driven modelingMining clinical dataComparative effectiveness research

Although many genetic markers are identified as being associated with Alzheimer's disease (AD), not much is known about their association with...

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Item Response Analysis of Alzheimer's Disease Assessment Scale

Verma, Nishant ;   Markey, Mia

Tags Biomedical data-driven modelingMining clinical dataMedical decision making

Alzheimer's Disease Assessment Scale-cognitive subscale (ADAS-cog) suffers from low sensitivity in detecting changes in Alzheimer's disease...

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Screening for Pre-Diabetes Using Support Vector Machine Model

Chung, Jai Won ;   Kim, Won Jae ;   Choi, Soo Beom ;   Park, Jee Soo ;   Kim, Deok Won

Tags Medical decision makingBiomedical data-driven modelingMining clinical data

The global prevalence of diabetes is rapidly increasing. Studies support screening and interventions for pre-diabetes, which results in serious...

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