Detection of Protein-Small Molecule Binding Using a Self-Referencing External Cavity Laser Biosensor

Zhang, Meng ;   Peh, Jessie ;   Hergenrother, Paul ;   Cunningham, Brian

Tags Optical and photonic sensors and systemsMicro- and nano-sensorsChemo/bio-sensing techniques

High throughput screening of protein-small molecule binding interactions using label-free optical biosensors is challenging, as the detected...

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Dynamic Modeling of the Hydrogel Molecular Filter in a Metamaterial Biosensing System for Glucose Concentration Estimation

Teutsch, Tanja ;   Mesch, Martin ;   Giessen, Harald ;   TarĂ­n, Cristina

Tags Optical and photonic sensors and systemsPhysiological monitoringBio-nano technology

We present a novel concept for ophthalmic glucose sensing using a biosensing system that consists of plasmonic dipole metamaterial covered by...

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Fabrication of Flexible Microlens Array through Vapor-Induced Room Temperature Dewetting on Plasma Treated Parylene-C

Bi, Xiaopeng ;   Li, Wen

Tags Micro- and nano-technologyOptical and photonic sensors and systemsMicrototal analysis and lab-on-chip systems

Microlens arrays have been widely used as an essential component in many optical systems. The conventional fabrication techniques, such as...

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Implantable Pulse Oximetry on Subcutaneous Tissue

Theodor, Michael ;   Ruh, Dominic ;   Subramanian, Sivaraman ;   Foerster, Katharina ;   Heilmann, Claudia ;   Beyersdorf, Friedhelm ;   Plachta, Dennis T.T. ;   Manoli, Yiannos ;   Zappe, Hans ;   Seifert, Andreas

Tags Optical and photonic sensors and systemsImplantable sensorsPhysiological monitoring

Blood oxygen saturation is one of the most prominent measurement parameters in daily clinical routine. However up to now, it is not possible...

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Optical Analysis of Lithium Carbonate: Towards the Development of a Portable Lithium Blood Level Analyzer for Bipolar Disorder Patients

May, James ;   Hickey, Michelle ;   Triantis, Iasonas F. ;   Palazidou, Eleni ;   Kyriacou, Panayiotis

Tags Optical and photonic sensors and systemsChemical sensors and systemsPhysiological monitoring

Lithium medication is the gold standard of treatment in Bipolar Disorder patients, preventing and reducing mood swings and suicidality. However,...

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Protein-Protein Binding Detection with Nanoparticle Photonic Crystal Enhanced Microscopy (NP-PCEM)

Zhuo, Yue ;   Tian, Limei ;   Chen, Weili ;   Yu, Hojeong ;   Singamaneni, Srikanth ;   Cunningham, Brian

Tags Optical and photonic sensors and systemsMicro- and nano-sensorsBio-nano technology

We demonstrate a novel microscopy-based biosensing approach that utilizes a photonic crystal (PC) surface to detect protein-protein binding...

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