Evaluating the Impact of Sequencing Error Correction for RNA-Seq Data with ERCC RNA Spike-In Controls

Tong, Li ;   Yang, Cheng ;   Wu, Po-Yen ;   Wang, May D.

Tags High throughput -omics data quality controlSequencing alignment, assembly, and analysis

Sequencing errors are a major issue for several next-generation sequencing-based applications such as de novo assembly and single nucleotide...

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Quantification of Cell Apoptosis for In-Vitro Colorectal Cancer Cell Cultures based on Morphological Features

Saribudak, Aydin ;   Kucharavy, Herman ;   Hubbard, Karen ;   Uyar, M. Umit

Tags Computational systems biologyBioinformatics for health monitoringBiomedical imaging marker extraction

Spatial properties of cell assays obtained by monitoring morphological characteristics of incubated cancer cells are studied as cell apoptosis...

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The Selection of Quantification Pipelines for Illumina RNA-Seq Data using a Subsampling Approach

Wu, Po-Yen ;   Wang, May D.

Tags High throughput –omic (genomics, proteomics, metabolomics, lipidomics, and metagenomics) data analytics for precision healthComputational molecular profilingGene expression pattern recognition

RNA sequencing, or RNA-seq for short, is widely applied for extracting gene and transcript expression from biological samples. Given numerous...

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